讲座报告主题：如何为柔性生物机器人的运动提供动力——智能水凝胶的多物理场建模
专家姓名：李华
日期：2025-03-07 时间：10:00
地点：能动学院千禧报告厅
主办单位：能源与动力工程学院

主讲简介：Dr. LI Hua (李华) is a full professor at the School of Mechanical and Aerospace Engineering, Nanyang Technological University, Singapore.  He was selected as a Fellow of the American Society of Mechanical Engineers (ASME) in 2019.  Dr. Li has been honored with numerous awards, including the Singapore HPC Silver Award in 2003, the top project at the SMI Forum in 2015, and the Scientist Award at the 9th ICCM in 2018.  He is also extensively funded by agencies, such as NRF, EDB, SMI and MPA, including the principal investigator of a computational BioMEMS project awarded under A*STAR's strategic research programme in MEMS, and by industries, including SUN Microsystems (Oracle), Sony, Philips, Lloyd's Register, Emerson, ABB, Makino, Rolls-Royce, DSO and JTC.  He has sole-authored a monograph book entitled "Smart Hydrogel Modelling" published by Springer, co-authored three monograph books entitled "Reduced Modelling of Planar Fuel Cells - Spatial Smoothing and Asymptotic Reduction" by Springer, "Meshless Methods and Their Numerical Properties" by CRC Press and "Rotating Shell Dynamics" by Elsevier, and 2 book chapters, one on MEMS simulation and the other on hydrogel drug delivery system modelling,  and sole-authored/co-authored over 200 articles published in peer-reviewed international journals.  In particular, he has so far worked on the theoretical modeling of hydrogel for +20 years, with more than 80 peer-reviewed journal papers relevant to the theoretical hydrogel modeling area.研究专长：柔性生物机器人。

主讲内容简介：智能生物材料的一个显著特征是它们能够响应某些外部生物刺激而变形。本文提出了一种新的生化-电-机械模型，通过固定脲酶的电离和变性状态，对脲敏感水凝胶在尿素外部刺激下的反应进行理论表征，其中模型包括固定电荷基团和温度以及pH对脲酶活性的影响。提出了一种新的反应速率来表征尿素的水解，该反应速率可以解释脲酶在环境条件下的电离和变性状态。通过与已发表的实验数据的检验，证实该模型可以很好地表征脲敏感水凝胶在尿素刺激下的响应行为，包括水凝胶内电位和pH的分布模式。研究结果表明，当水凝胶与富含尿素的溶液（如人类尿液）接触时，可以通过酶诱导的pH值和电位梯度产生电能。

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